This line is devoted to studies evaluating the efficacy, effectiveness and safety of health interventions such as immunobiological and other medical technologies proposed for individual clinical use or in health programs, as well as validation studies of diagnostic methods and Measured in health in general. It is articulated to produce applications in health programs and policies through the search, analysis and synthesis of scientific evidence to support choices of safe and effective interventions.

This line of research conducts interdisciplinary approaches and investigations on the problems that emerge in the construction and application of epidemiological knowledge. It is essential to consider that epidemiological knowledge is essential in the configuration of health practices, both in the strict sense of evaluating etiological hypotheses and medical technologies; As in the broad sense of information, communication, prevention, health promotion. Another aspect to be taken into account is that of the epidemiology to operate, besides its own concepts, also contents coming from other scientific fields. The purposes of this line are: to understand the sociocultural implications of epidemiological research; To establish links between epidemiology and social studies of science and technology; To study, in historical and philosophical perspective, the origin and transformations of the concept of health, disease, epidemic, risk, causality, responsibility.

The main objective of this line is to study the social and environmental determinants of endemias, based on a perspective that incorporates methods and categories of analysis of different disciplines, such as epidemiology, ecology, social sciences and geography. It develops health situation studies, trend monitoring and research models on the relationships between social development, socio-spatial organization and processes of disease production and control.

It comprises the theoretical discussion and studies related to the various dimensions of development - political, economic and social - and its interfaces with health, with emphasis on the following themes: role and patterns of State performance in development and social protection in health; Training and models of development and social protection in health in comparative perspective; Implications of the political system (federalism, relations between Powers) for development and social protection; Regional development and health; Challenges to social protection in the face of global change, the emergence of new risks and inequalities; Repercussions of the State Reform processes for development, social protection and health.

The research line covers projects aimed at understanding the health problems of the subaltern classes based on their practices and conceptions, both in the cities and in the countryside. The theoretical-methodological perspective that guides the studies is the Freireana grassroots popular education, where participatory forms of research and social intervention are favored, adapted to an expanded conception of health surveillance. The studies included in this line are intended to understand the poverty situation and the survival tactics of the subaltern classes. It highlights the search for complementary or alternative resources to health services that address the health-disease-care process, such as popular religiosity and social groups that enhance resources and social support networks.

This line of research makes the laboratory diagnosis of communicable diseases, using established techniques and incorporating new technologies, as essential components to surveillance actions.

This research line involves different theoretical and methodological approaches and its main objective is the production of knowledge that contributes to the improvement of the effectiveness, efficiency and quality of health policies, systems and programs. The challenge is to account for the complexity that permeates and mediates actions and interventions in the field of health, as well as the achievement of results. The investigations of this line include the steps of defining and prioritizing problems, the interventions and strategies of approach chosen, their determinants, the resources involved, the results achieved, expected and unexpected, as well as the influence of the context in the directions of the whole process , Which includes the formulation, implementation, monitoring and evaluation of health policies and programs

With a view to subsidizing policy formulation and health service management, this research line covers studies on the use, quality and costs of health services and technologies, as well as studies of factors that explain variations in these aspects. In the quality approach, the dimensions of effectiveness, effectiveness, efficiency, access, continuity, safety, fairness and adequacy are considered.

It includes studies on the process of formulation and implementation of public policies, dissemination of normative guidelines in policies through international agencies, communities of specialists and national actors, federative relations and between the powers and their interface with health, participation of different social groups in the health policies. It analyzes the configuration of institutional arrangements and conditions of conduct, implementation and veto, by state actors, interest groups and / or social movements, government policies that affect health conditions, the environment and access to services, programs And public goods.

The present line of research studies the gender issues related to the field of Collective Health, using a sociological approach that covers issues of production and reproduction.

This line of research aims to: analyze and discuss the relationship between the dynamics of globalization and its impact on the health of populations at national and international levels; Identify and analyze the interrelationships between international relations and health; Produce the necessary knowledge to support the discussion on international relations and health and support the implementation of policies aimed at the well-being of humanity; And train professionals to work in the area of global health and health diplomacy.

This line of research is organized around the conceptual and empirical questions posed by the demands from the various representative bodies of the workers and public agencies responsible for Workers' Health. The study proposals in this field are based on the formation of networks of political and institutional articulation, in which the planning, implementation and evaluation of actions are guided by a participatory process, stimulating social and institutional practices that transform health and work conditions .

This line of research develops studies that are grouped into eight axes: (i) Macroeconomic policies and health sector reforms; (Ii) Public sector economics and health system financing; (Iii) fiscal federalism and health financing; (Iv) Methods of intergovernmental allocation of resources within the health system, from the perspective of equity; (V) Resource allocation systems for health service providers; (Vi) Analysis of the supplementary health system; Instruments of regulation of the operators on the providers of health services; Relations between the public and private systems; (Vii) Economic evaluation of health programs.

The purpose of this research area is to analyze, in a comparative perspective, the process of historical development of health policy, structuring and reforming service systems. The main objective is to study the specificity of health policy in the context of social policy and to analyze, in a comparative perspective and from the study of selected cases, the nature of state intervention in the sector and its dynamics in time and space; The political and institutional arrangements that enabled the organization of the different health systems; The trends of reform and the models that they advocate in specific historical periods. It is a transdisciplinary area and works with different methodological approaches and research techniques, to account for both the complexity of the object under study and the variability of the health system policy and organization patterns in the different countries, whether in the North or in the South .

This research line is an interdisciplinary field of knowledge and practices that addresses the health-disease process and its relations with the corresponding public policies, the environment, health care and social participation. It develops in two dimensions: analysis of discourse and practices around health promotion; And development of own perspectives that translate into strategies for studying health situations, elaboration of interventions and construction of evaluation methodologies.

This line of research addresses the issue of production and consumption of health goods and services, their effects on health, and the role of the state as a promoter and regulator. In Law 8.080 is the definition of sanitary surveillance, being a set of actions capable of intervening in health problems arising from the environment, production and circulation of goods and the provision of services of health interest in order to prevent risks the health. Its action encompasses all stages of the production / consumption process and, in addition to its action on chemical, physical and biological determinants, deals with the inherent inequality in production / consumption and work / health processes. The research relates, on the one hand, to the discussion of health surveillance policies and the institutional arrangement for sanitary regulation, its planning and management, and the evaluation of actions and services, technologies and health programs. On the other hand, they relate to the identification, management and communication of risk seeking social participation, the transformation of social practices and the improvement of the quality of life.

Considering housing all the built space that is part of a citizen's life, such as residence, school, hospitals, etc., this line aims to apply the concept and methodology of healthy housing in SUS practices, mainly within the scope of the Health Program of Family, starting from the housing to carry out a more comprehensive analysis of the health of each family that inhabits it. On the one hand, the constructed space and its surroundings are evaluated from a biosafety point of view, seeking to identify risk factors for human health and the environment. On the other, it observes the relationship between habitable patterns regionally in Brazil and its relationship with the endemic diseases of these regions. Finally, this line considers that from the healthy housing, it is possible to improve the indicators of morbimortality and the health of the Brazilian population.

This line of research aims to describe and analyze, through theoretical and empirical research, the health framework of indigenous peoples in Brazil and other regions, approaching it from a historical, anthropological and epidemiological perspective. It emphasizes the analysis of the socioeconomic, cultural and environmental changes on the disease health process, as well as the directions of the public policies related to the health care of these peoples.

It is oriented both to the analysis of the characteristics and obstacles to the improvement of the quality of health information, the power relations and production of knowledge that consubstantiate the National Health Information Policy and the methodological and technological principles of Health Information Management; As well as for the production of information in the formulation, implementation and evaluation of health policies and interventions.

We highlight in the amendment three central aspects of Public Policy analysis: (1) the formulation process, its scope and relevant actors, as well as the relationship between the decision-making process and the implementation, considering the nature of the Brazilian federation - National and subnational levels - and the relationships between executive, legislative, judicial and prosecutor; (2) the study of government institutions, from the perspective of historical institutionalism, contributing to the understanding of the institutional legacies that interact in the implementation of public policies present in the aforementioned spheres of government; And (3) corporate participation, incorporating new actors into the decision-making process of public policy and requiring theoretical approaches and studies on actors and social movements and their articulation in corporate bodies and / or organizations.

This line of research covers topics of epidemiology, social policies, history of knowledge and institutions in the field of Mental Health. It deals, with particular interest, with research on the distribution of mental disorders in population groups and their risk factors, as well as on the design, analysis and meta-analysis of clinical trials in psychiatry. This area also covers research on recent and contemporary trends in deinstitutionalization and psychiatric reform, public policies on mental health and psychiatric care, as well as techniques and trends in the planning, organization and management of mental health services and systems.

This line of research includes studies on the origin and evolution of diseases and infections, from prehistory to the present day. They are remnants of missing populations whose vestiges bring information about aspects of health, disease and adaptability over time. Techniques and methods suitable for research in archaeological materials are developed. It seeks to understand how the various pathogens have succeeded, in an evolutionary perspective, until their constitution in the present time.

The National Medicines Policy (Portaria 3916/98) and Resolution CNS 338/04 define the theoretical frameworks of Pharmaceutical Assistance (FA) in Brazil, pointing it as a conceptual and practical field, and defining it as a group of activities that Are related to the medicine and whose purpose is, in view of the demands of users, patients and communities, to support the health actions directed at them. It has multiprofessional vocation, acting and interacting in several points of health care. With regard to its purpose, this line overlaps the evaluation of health services, programs and systems, the evaluation of health technologies for pharmacoepidemiology, including drug use and pharmacovigilance studies, economic evaluation of medicines, hospital pharmacy, Management of pharmaceutical care, health surveillance of medicines and services, rational use and drug policies.

This line of research is devoted to the study of national systems of science, technology and innovation in health. The main themes are: the evolution and dynamics of the industrial health complex and the different productive segments; The policies of science, technology and innovation in health; Institutional development; Mechanisms of incentive, induction and regulation in the area; The organizational innovations associated with the production of technological goods and services in health; The assessment of technological and economic trends; The scientific, technological and managerial capacitation of ST & I organizations in Health; And the development of models, methodologies and tools for planning and management of ST & I activities in Health.

This line of research is located in the fields of Sociology and Labor and Education Management. It involves three major areas: the sociology of professions, the world of work; The management of work and education in the health sector. It develops research focused on aspects of work in general, work and education management, the quality of worker training, the development of innovative teaching methods, including the teaching-learning processes provided by the intensive incorporation of Information and Communication Technologies , As well as for the contemporary aspects of the sociology of professions.

The discussion between the health and legal sciences has sought to build an integrated knowledge, which addresses issues related to Law, Health and Citizenship. The construction of this line of research is based on the importance of the theme and the need for its academic approach, based on the idea that it is necessary for Health to appropriate the instruments of Legal Science and that it owns knowledge of Health. The area of Law and Health, integrating several disciplines, aiming to contribute to the improvement of health conditions, having as a priority the construction of citizenship, which goes beyond the scope of the individual and as a space for the achievement of human rights in the Public health.

The main objective of this line of research is the use of quantitative models in the analysis of complex issues, such as the contextual effect on the individual, whether the place of residence or medical care, and the multiple measures and individual responses, aiming at a Better understanding of processes relating health and disease and care and populations, including demographic and ecological issues.

This line of research turns to the complexity of the problems related to the management of public health services and the quality of care, specifically considering the group / intersubjective and unconscious characteristic of organizational processes, which has an important impact on the dynamics of health services And in its quality. It includes research aimed at: a) the analysis of the implications of sociability patterns and the predominant modes of subjectivation in contemporary society on collective processes, and particularly on health management and work; B) the examination of planning and management devices in light of the intersubjective and unconscious processes present in health organizations; C) the examination of group processes as a device for analysis and intervention in health organizations; D) the analysis of health organizations in their imaginary and symbolic dimensions and the limits and possibilities of change processes; E) analysis of the impact of planning and management strategies and devices on the quality of health care; F) the investigation of the intersubjective and unconscious characteristic of health work and its consequences on the quality of care and cooperation; And g) the investigation of the organizational process from its intersubjective, imaginary and unconscious dimension and its implications on the leadership function and the exercise of cooperation.

This line of research focuses on the analysis of the toxicity of drugs, environmental pollutants and natural substances of public health interest. It includes: (1) biotransformation studies of xenobiotics in parasitic diseases and inflammatory processes; (2) safety assessment (genetic and reproductive toxicity and drug kinetics investigation) of drugs for neglected diseases; (3) studies of the effects of environmental pollutants on organisms integrating aquatic ecosystems, with the development of biomonitoring and biomarkers of pollution from aquatic environments; (4) evaluation of reproductive toxicity, carcinogenicity, endocrine toxicity and neurobehavioral toxicity of pesticides and industrial pollutants; And (5) toxicological studies of natural products, considering the evaluation of their effects on xenobiotic biotransformation enzymes.

The line of research "Violence and Health" aims to study the impact of violence on the health of the population. Its importance is supported by the high morbidity and mortality rates due to accidents and violence in Brazil and by the range of physical, emotional and social consequences it causes. The approach of the theme is made through quantitative and qualitative methodologies, requiring a multidisciplinary perspective. The study of the impact of violence on health involves: (1) several phases of health service delivery (health promotion, prevention, treatment and rehabilitation); Different specific and vulnerable groups; (3) improving health care and management to care for victims of violence.

It aims to study the determinants of health conditions and access to health services of the maternal and child population, as well as to identify the conditions of the structure and processes involved in the health care of this population group. In this line, several research projects on gestation, prematurity, low birth weight, maternal and perinatal morbidity and mortality, evaluation of prenatal and delivery services, child and adolescent health were developed or are under development, using data Or from the National Information Systems.